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Longer sleep duration linked to progression of diabetic nephropathy

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Longer sleep duration linked to progression of diabetic nephropathy

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For adults with type 2 diabetes, longer sleep duration is associated with an increased risk for incidence and progression of diabetic nephropathy, according to a study published online Oct. 8 in the Journal of the Endocrine Society.

Fuki Ikeda, from Juntendo University Graduate School of Medicine in Tokyo, and colleagues examined the association between sleep duration and a composite end point of incidence and progression of diabetic nephropathy in a study involving 678 Japanese outpatients aged 25 years and older and younger than 70 years with type 2 diabetes. At baseline and at years 2 and/or 5, lifestyle habits were assessed and mean values of lifestyle factors were calculated.

The researchers found that 215 participants experienced the end point during a follow-up of 6.0 ± 2.7 years. Mean sleep duration was the only lifestyle factor associated with the end point. The multivariable-adjusted hazard ratios were 1.08, 1.56 and 1.92 for mean sleep duration of 6 to <7, 7 to <8 and ≥8 versus <6 hours, respectively. After adjustment for key lifestyle and diabetes-related factors, this association remained significant. In older participants and those with microalbuminuria or reduced kidney function, the association was stronger.

, also from the Juntendo University Graduate School of Medicine, said in a statement.



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