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About 10% of cancers are linked to an inherited genetic variant, but as few as one in 15 cancer patients eligible for genetic testing complete it.

In a new study from researchers at the University of Michigan Rogel Cancer Center, an online resource and phone-based coaching both helped increase rates of genetic testing, suggesting that innovative ways to deliver information combined with motivational messaging could help move the needle.

"Many barriers exist to genetic testing, including access, cost, privacy concerns and fear. Scalable strategies are needed to overcome these barriers and better facilitate genetic testing," said senior study author Elena Stoffel, M.D., M.P.H., clinical professor of internal medicine/gastroenterology at Michigan Medicine and director of the Cancer Genetics Clinic at the Rogel Cancer Center. The grant was co-led by Jennifer J. Griggs, M.D., M.P.H., and Ken Resnicow, Ph.D.

The study engaged 793 adults from across Michigan who met clinical criteria for genetic evaluation based on their personal or family history of cancer. Participants were randomized to receive phone-based health coaching, a self-directed digital intervention or usual care. The two interventions included education about genetics and motivational interviewing concepts.

Overall, 5% of participants completed genetic testing after six months and 10% completed testing after a year. Those who received either intervention were more likely to complete testing or to report that they intended to seek testing, compared to those receiving usual care.

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