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Excessive polypharmacy and complex medication regimens are associated with greater physician burden

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Excessive polypharmacy and complex medication regimens are associated with greater physician burden

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Patients receiving home-based medical care are often older adults with multiple chronic conditions, and polypharmacy, commonly defined as the concurrent use of multiple medications, is prevalent in this population. However, the challenges of medication management extend beyond the number of prescribed medications.

Factors such as dosing frequency, dosage forms and special administration requirements can make medication regimens more difficult to manage for both patients and health care professionals. Although polypharmacy and complex medication regimens have been associated with increased treatment burden and medication-related problems, their relationship with the perceived clinical burden of physicians providing home health care has remained unclear.

To address this knowledge gap, researchers examined 503 patients receiving home-based medical care at seven medical institutions in Tokyo and Ibaraki Prefecture, Japan. The research team assessed both the number of prescribed medications and the complexity of medication regimens and investigated their associations with physicians' perceived clinical burden.

The results showed that physicians experienced a significantly greater burden when caring for patients with excessive polypharmacy, defined as the use of 10 or more medications, and those with particularly complex medication regimens. These associations remained significant after adjustment for factors including patient age, comorbidities and consultation time.

The findings suggest that improving medication management in home health care requires attention not only to reducing unnecessary medications but also to simplifying medication regimens whenever clinically appropriate.

The researchers also highlighted the potential benefits of multidisciplinary collaboration, particularly between physicians and pharmacists, in optimizing pharmacotherapy, reducing physician burden and ensuring safe and effective treatment for patients receiving home-based care.


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