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People with type 2 diabetes were much more likely to achieve remission after weight-loss surgery than after intensive medical and lifestyle management, according to a long-term study. Researchers also identified patient characteristics linked to remission and to the likelihood of diabetes returning.

The study, published in Diabetes Care, found that 58% of participants assigned to metabolic-bariatric surgery achieved diabetes remission, compared with 3% of those assigned to medical and lifestyle management. Participants were followed for a median of 11 years, with some followed for up to 14 years.

Researchers found that people who had lived with diabetes for fewer years, did not use insulin and took fewer types of blood sugar-lowering medications before treatment were more likely to achieve remission. Greater weight loss during the first year after treatment was also associated with a higher likelihood of remission.

The Alliance of Randomized Trials of Medicine vs. Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) is the largest, longest-running trial of metabolic surgery for diabetes. , of Brigham and Women's Hospital and Harvard Medical School in Boston. The principal investigator is John P. , who this summer was named executive director of the University of Oklahoma Health Harold Hamm Diabetes Center. Kirwan also serves as vice provost for diabetes programs at the University of Oklahoma and holds the Chickasaw Nation Endowed Chair in Diabetes Research.

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