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Cancer incidence remains higher in people with type 2 diabetes, with the gap widening in recent years

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Cancer incidence remains higher in people with type 2 diabetes, with the gap widening in recent years

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A nationwide study presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2 has found that people with type 2 diabetes (T2D) have a higher risk of developing cancer. Cancer incidence has risen more among people with T2D than among those without diabetes over the past 25 years, largely driven by obesity-related cancers.

Based on data from the entire adult population of Denmark, the study found that overall cancer incidence was 12% higher among men with T2D and 22% higher among women with T2D than among those without diabetes in the most recent period (2010–2022). The corresponding differences between 1996 to 2009 were 9% and 15%.

"Our findings underline the growing cancer burden among people with T2D and highlight the need to prioritize cancer prevention and early detection as part of long-term diabetes care," said Dr. Tinne Laurberg of Steno Diabetes Center Aarhus at Aarhus University Hospital in Denmark, who led the research.

"This is especially important for common obesity-related cancers, such as colorectal and postmenopausal breast cancer, for which screening programs already exist in many countries. We must ensure that people with T2D benefit fully from these established programs by encouraging greater participation."

Cancer is a major health condition associated with T2D. Prolonged exposure to high blood sugar and insulin levels, as well as insulin resistance and ongoing inflammation, may contribute to cancer development.


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