The Doomsday clock is ticking away. In just over a month, "Avengers: Doomsday” will land in theaters. The arrival of Robert Downey Jr.’s Victor von Doom promises to shake up the Marvel Cinematic Universe in a big way. This could mean waving goodbye to some beloved MCU heroes, because it’s hard to see every single Avenger surviving Doomsday.

“Avengers: Infinity War” saw the Marvel roster ruthlessly culled in a snap of Thanos’ fingers. While most of the heroes were un-blipped in the epic follow-up “Avengers: Endgame,” some deaths have proved rather more permanent, like Black Widow and, of course, Tony Stark, aka Iron Man.

I’m expecting “Doomsday” to have a similarly sizable impact on the MCU, maybe even a bigger one as Marvel looks to get back on track following its wilderness years post “Endgame.” Speculation about who will live and who will die is reaching a fever pitch, so I’m looking at the odds (courtesy of Polymarket) and making a few personal predictions.

Based on Polymarket’s current data (as of Nov. 10), Loki (Tom Hiddleston) is most likely to kick the bucket in “Doomsday,” with his brother, the God of Thunder himself, in second place. If both these predictions came true, Doomsday would be particularly brutal on the Thor family.

Spider-Man comes in third — an interesting prediction considering Spidey isn’t actually confirmed to appear (but is rumored). Sam Wilson (Anthony Mackie), who’s taken up the mantle as Captain America, and Ant-Man (Paul Rudd) round out the top five, and the death of either character would hit longtime viewers hard, as Mackie and Rudd have been MCU staples for years.

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