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Preliminary findings link long-term vaping to persistent changes in lung function

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Preliminary findings link long-term vaping to persistent changes in lung function

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Long-term vaping in young people may induce persistent changes in lung function, suggest preliminary findings published online in the journal Tobacco Control. Further research is needed, emphasize the researchers. But the cumulative effects might heighten the risk of life-limiting chronic obstructive pulmonary disease (COPD), a hallmark of which is loss of lung function—and specifically, a decline in forced expiratory volume in the first second (FEV1)—say the researchers.

To explore this further, the researchers analyzed the results of lung function tests given to 22 people aged 21–35 who currently used primarily e-cigarettes at the start of the study and again an average of 12 months later.

Participants provided information on the frequency of daily vaping and took the lung function tests between 9 and 11 a.m., 12 hours after using any tobacco product.

The tests measured FEV1, which assesses how much air can be blown out of the lungs in one breath in 1 second; forced vital capacity, which assesses the total volume of air that can be forcefully and rapidly exhaled from the lungs after taking a deep breath; and the ratio of the two.

In the second test, the results indicated a significant reduction in FEV1. And after adjusting for vaping frequency and potentially influential factors, such as age, sex, race and height, there was a declining trend in FEV1 as the amount of daily vaping increased, although this wasn't statistically significant.


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