CONNECT WITH US
HealthTech

HealthTech

Postoperative complications elevated for patients with systemic lupus erythematosus

Medical Xpress logo

Published on

Add as a preferred source on Google
Postoperative complications elevated for patients with systemic lupus erythematosus

This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:

Patients with systemic lupus erythematosus (SLE) have an increased risk for postoperative complications, according to a study published online Oct. 9 in Rheumatology International.

Francisco Eduardo Silva, M.D., and Mirhelen Mendes de Abreu, M.D., Ph.D., from the Universidade Federal do Rio de Janeiro in Brazil, conducted a nationwide retrospective matched cohort study to compare postoperative outcomes between patients with SLE and matched controls. The cohort included 1,708 patients with SLE and 8,540 controls.

The researchers observed associations for SLE with increased risks for surgical, clinical, infectious and other procedure- or care-related complications (risk ratios, 2.20, 3.30, 3.66 and 11.33, respectively). SLE was associated with obstetric complications among patients undergoing obstetric procedures (risk ratio, 1.87). Cardiovascular risk was independently associated with higher odds of clinical and other procedure- or care-related complications within the SLE cohort (adjusted odds ratios, 2.75 and 5.46, respectively). In both sensitivity analyses restricted to elective procedures and excluding patients classified with cutaneous lupus, the associations between SLE and surgical, clinical and infectious complications remained significant.

"These findings identify a higher-risk perioperative profile in this population, while the relative contributions of underlying disease activity and immunosuppressive treatment warrant further investigation," the authors write.

, Higher postoperative complication rates in patients with systemic lupus erythematosus undergoing surgical and obstetric procedures: a nationwide retrospective matched cohort study, Rheumatology International (2026).



Source link
Related Topics:HealthTech

Disclaimer

We strive to uphold the highest ethical standards in all of our reporting and coverage. We TheMorningPulse.fyi want to be transparent with our readers about any potential conflicts of interest that may arise in our work. It's possible that some of the investors we feature may have connections to other businesses, including competitors or companies we write about. However, we want to assure our readers that this will not have any impact on the integrity or impartiality of our reporting. We are committed to delivering accurate, unbiased news and information to our audience, and we will continue to uphold our ethics and principles in all of our work. Thank you for your trust and support.