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The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals

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The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

GLP-1 weight-loss drugs are one of the biggest biotech breakthroughs of the last decade. But to some clinicians, they can represent something sinister—a potential trigger for eating disorders.

A new report suggests the global incidence of anorexia nervosa and bulimia nervosa shot up by 71% between 1990 and 2023. And clinicians are already seeing GLP-1s exacerbate the issue.

This story is from The Checkup, our weekly biotech newsletter. Sign up to receive it in your inbox every Thursday.

—“Love is Infrastructure” is a short fictional story by Charlie Jane Anders, author of a forthcoming novel titled Good Things Are Coming Your Way.

Mainspring and St. Barnabas are two neighboring cities with different personalities. They’ve never particularly liked each other, but that changes when both develop minds of their own, shaped by the votes of their residents.

As the cities begin to fall for each other, a third city enters the picture. Turnbull promises Mainspring a more efficient future, but its vision of urban life comes with a troubling price.

Read the full short story about self-aware cities, direct democracy, and a steamy romance.

This story is from the latest edition of our print magazine. Subscribe now to get every issue as soon as it lands.

Used for decades in everything from nonstick pans to firefighting foams, PFAS, or “forever chemicals,” are linked to increased risks of fertility challenges, developmental delays, cancer, and reduced immune response.


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