Twenty founders just earned their shot at Disrupt glory. They’re headed to the Disrupt Stage at TechCrunch Disrupt to compete for the $100,000 prize and the coveted Disrupt Cup.

Every year, thousands of founders from around the world pitch us on what they believe the future should look like. This year’s Top 20 are building it from organs to orbit and everywhere in between.

Across this cohort, one theme kept emerging: Making the previously invisible measurable.

These founders are finding ways to understand signals we couldn’t previously capture, model systems too complex to predict, and turn the physical world into data that machines can actually act on. They’re measuring the biological clocks inside our bodies and growing miniature human organs in labs. They’re teaching robots to take on increasingly complex physical work and modeling the real world closely enough to predict what might happen next — even the behavior of wild animals. They’re extracting intelligence from scam calls and finding new ways to use the computing power already orbiting above our heads.

And then, of course, there’s the company trying to launch cargo into space with a giant hydrogen-powered cannon.

What connects these 20 companies isn’t a single technology or industry. It’s an ambition to understand more of the world around us — biological, physical, industrial, and digital — and use that understanding to make better decisions, automate what once required human intervention, and tackle problems that previously seemed too complex to solve.

Now they have six minutes on the Disrupt Stage to prove it.

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