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A research team led by Dr. Lee Da young, Dr. Nan Hee Kim of the Division of Endocrinology and Metabolism (Department of Internal Medicine, Ansan Hospital), Dr. Lee Heon-jeong of the Department of Psychiatry (Anam Hospital) and Dr. Lee Jung-been of the Division of Computer Science and Engineering (Sun Moon University) announced findings indicating that circadian rhythms (biorhythms) are closely related to blood glucose control in patients with type 2 diabetes.
The research analyzed the relationship between circadian rhythms and blood glucose changes using CGM and wearable activity monitors.
The research team studied 122 patients with type 2 diabetes who received insulin treatment at Ansan Hospital from 2021 to 2024. The participants wore CGM devices and wearable activity monitors for 10 days. The team collected data related to their circadian rhythms, including blood glucose changes, sleep times, physical activity levels and heart rates.
The analysis showed that 46.3% of patients in the group with the most stable circadian rhythms achieved their blood glucose management goal. That rate was approximately 2.3 times as high as the rate for the group with the least stable rhythms (20.0%). Even after accounting for factors such as age, BMI and HbA1c, greater circadian rhythm stability was associated with a higher probability of achieving blood glucose management goals.
The correlation between activity and blood glucose management also differed depending on the time of day.
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